Antioxidant activity of chitooligosaccharides upon two biological systems: Erythrocytes and bacteriophages

Most of the reports to date on the antiox based on strictly chemical methods. Whe method used to evaluate the antioxidant antioxidant might have a protective effec mixtures and a low MW chitosan (LMWC phages, subjected to accelerated oxidatio Our results suggest that COS/LMWC ca compounds reduced either the hemolytic ever, the results obtained for these biolo chemical assay, suggesting that the prote enhancement of the oxidative damage – Abbreviations: ROS, reactive oxygen species; Hb, h (2-amidinopropane) hydrochloride; PFU, plate formin culture collection; ABTS, [2,2-azinobis(3-ethylbenzo DPPH, 2,2-diphenyl-1-picrylhydrazyl. * Corresponding author. Tel.: +351 22 5580004; fax E-mail address: [email protected] (F.X. Malcat pacity of chitosans and chitooligosaccharides (COS) are ing antioxidants with potential in vivo applications, the should be representative of the conditions in which the is work we evaluate the antioxidant activity of two COS two biological oxidizable substrates – erythrocytes and